Colby Lewis: 12 SO, 5 HR

First time it's ever happened. 12+ SO with 4 HR did happen 3 times previously (since 1919):

http://www.baseball-reference.com/boxes/PIT/PIT195008271.shtml
http://www.baseball-reference.com/boxes/NYN/NYN196208020.shtml
http://www.baseball-reference.com/boxes/ATL/ATL199706280.shtml